Chinese scientists prove that same-sex mammals can also achieve reproduction
October 19, 2018 Source: World Wide Web
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];According to foreign media reports, a group of scientists from China have successfully cultivated the next generation through the DNA of two homosexual mice. This is the first time such a feat in the mammalian world that it will have a huge impact on humans. The researchers' recent article in ScienceDirect introduces this extremely complex process.
In the process of creating same-sex offspring, the team used a pair of father and a pair of mother DNA sequences to test and achieve varying degrees of success.
The offspring obtained from the double mother DNA edited by CRISPR were found to be healthy, and the scientists pointed out that the offspring obtained in this way are no different from the mice born under normal conditions. However, the double father mice did not have strong adaptability. Only about 2% of the experiments in the experiment were successful, and none of them survived for a few days.
The way the team is cultivating same-sex offspring is not what most people think of. SingularityHub's Shelly Fan calls it the "Frankenstein (Frankenstein) Law."
To breed offspring of same-sex animals, the team mutated cells carrying specific DNA to carry only half of the normal information, and these cells were called "haploid cells." The reason why only half of the normal information is left is because they can combine with the cells of another mother to form a finished fertilized egg. The resulting "mother and mother" cells are then mixed into the uterus of the surrogate mouse mother, and the next process is the same as the normal birth process. Finally, the team was able to produce 29 live mice in 210 embryos.
However, this situation cannot occur in the cultivation of the descendants of fathers and fathers. It is understood that cultivating the next generation through male homosexuality is much more complicated and the failure rate is very high. Because male mice have no eggs, and it is an important part of the mammal's breeding process to date, the research team used an egg from a female mouse. They basically hollowed out the contents of the egg, removed the existing NDA inside and filled it up. However, unfortunately, none of the descendants from the two fathers survived.
Scientists clearly have a lot of work to do before this breakthrough study begins to have an impact on human fertility and reproductive science. Perhaps in the future, ancient mammalian reproductive models will no longer be the only effective solution.
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