The special compound flavanol in cocoa may significantly improve the health of the individual's cardiovascular system
October 17, 2016 Source: Bio Valley
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];The taste that chocolate brings to its hobby is everywhere, but many recent studies have found that the compound called flavanols in cocoa powder seems to be beneficial to the health of the cardiovascular system, published in an international magazine. In the research report of the Journal of Nutrition , researchers from Brown University conducted a systematic analysis and retrospective study of 19 randomized controlled clinical trials of cocoa consumption. The researchers focused on the analysis and compared with the control group. In terms of agents, the consumption of cocoa products rich in flavanols is associated with improvements in specific circulating biomarkers in the individual's cardiovascular metabolic system.
In this study, researchers conducted a study of 1,139 volunteers. The researcher, Professor Simin Liu, said that a comprehensive analysis of these clinical trials revealed how cocoa flavanols affect biomarkers of cardiovascular metabolism in the body. It provides clues for the design of large-scale preventive trials to protect patients from diabetes and cardiovascular disease; we found that cocoa flavanol intake can reduce abnormal blood lipids, insulin tolerance and systemic Inflammation, which is a major subclinical risk factor for cardiovascular metabolic diseases.
The researchers point out that there may be some limitations in clinical trials. All studies are relatively small in scale and have a short duration. Not all biomarkers tracked in the study can be improved, and no studies have been conducted. It is possible to directly detect whether the consumption of flavanols in cocoa can reduce the onset of heart disease and the development of type 2 diabetes in individuals. When the heterogeneity between individuals was considered in the study, the researchers summarized the results from 19 clinical trials and found that cocoa-rich cocoa products did have some benefit for cardiovascular health.
According to the researchers, according to the level of cocoa consumption, we found that 200 to 600 mg of flavanols per day were able to achieve optimal cardiovascular protection, and researchers also found blood glucose and insulin levels in volunteers. The decline, as well as a decline in the level of insulin tolerance called HOMA-IR, the researchers also said that the level of beneficial cholesterol in the participants' bodies increased; among the participants in the high-level intake of flavanol participants It was found that its insulin resistance was significantly improved, and triglyceride levels were also decreased, but no significant increase in beneficial cholesterol levels was observed; in the participants of low-dose flavanol intake participants, the researchers only observed It is obvious that there is an effect of intentional cholesterol.
In general, the beneficial effects of flavanols do not vary from male to female, and do not depend on the physical form of the flavanol-rich cocoa product, such as dark chocolate and beverages. Researcher Lin said that the clinical treatment group in our comprehensive analysis mainly consumes black chocolate, some of which are made from cocoa powder, so the results of current research may not be extended to different chocolate candies. Or white chocolate, because the additives such as sugar in these foods are significantly higher than the level of black chocolate.
The final investigators concluded that our study highlights the need for large-scale, long-term, randomized, controlled trials that can help improve our understanding of the long-term benefits of coronol intake in cocoa on cardiovascular biomarkers, and this Will be able to transform into clinical results, and provide new clues and ideas for the development of new therapies to combat cardiovascular disease.
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