Tramadol Hydrochloride Sustained Realease Tablet

Tramadol hydrochloride sustained release tablet 100mg
Ingredients
The active ingredient of this product is tramadol hydrochloride.
Chemical name: (±)-E-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride.
Molecular formula: C16H25NO2·HCl
Molecular weight: 299.84
Character 
This product is white or almost white, one side has a dividing line of special-shaped film pieces.
Indications
For moderate to severe pain.
Specification 
100mg
Dosage
Swallow and do not chew.
The amount of this product depends on the degree of pain. It is generally taken from 50 mg (half tablet) each time and once every 12 hours. The dosage can be adjusted according to the patient's pain level. Normal adult and moderately painful patients over 14 years old, a single dose of 50 ~ 100mg (half -1 tablets). Children over 1 year of age who weigh not less than 25 kg are given a dose of 1 to 2 mg per kilogram of body weight. The minimum dose of this product is 50 mg (half tablet). The daily maximum dose usually does not exceed 400 mg (4 tablets). Higher doses may also be considered when treating cancer pain. Liver and kidney insufficiency should be used as appropriate. The dose of elderly patients should be considered reduced. The interval between two medications should not be less than 8 hours.
The above recommended dose is for reference only, in principle, the lowest dose of analgesia should be used. Take as directed by your doctor.
Adverse reactions
This product has adverse reactions:
1. Systemic: allergy, allergic reactions;
2. Cardiovascular system: hypotension, tachycardia, very rare hypertension and bradycardia;
3. Digestive system: nausea*, vomiting*, constipation*, gastrointestinal dysfunction, dry mouth*;
4. Central nervous system: dizziness*, drowsiness*, headache, visual abnormalities, emotional instability, euphoria, hypoactivity, hyperactivity, cognitive and sensory disturbances, convulsions, confusion, drug dependence, hallucinations, withdrawal synthesis Signs include: Excitement, anxiety, nervousness, insomnia, hyperkinesia, tremors, and gastrointestinal symptoms;
5. Skin: sweating*, pruritus, rash, urticaria, angioneurotic edema;
6. Urogenital system: urination disorders, urinary retention;
7. Respiratory system: dyspnea, bronchospasm, respiratory depression. (Note: * is a common adverse reaction with an incidence of ≥ 1%)
Contraindication 
People who are highly sensitive to this product and who are acutely poisoned by alcohol, sleeping pills, analgesics or other psychotropic substances.
Precautions
1. This product is used with caution in people who are opioid dependent or have drug abuse and dependence; acute alcoholism and use of sleeping pills, central analgesics (including opioids and psychotropic substances); in combination with central nervous system sedatives and When shock occurs; Monoamine oxidase inhibitors are being used or used within the past 14 days; Severe liver or kidney function damage; Head injury, increased intracranial pressure, confusion of unclear consciousness, respiratory and respiratory disorders, and respiratory depression.
Seizures have been reported to occur at therapeutic doses, and the risk of seizures may increase when the dose exceeds the conventional daily dose limit. For patients with a history of epilepsy or who are prone to attack, use it only as a last resort. Patients taking both tramadol and drugs that reduce seizure thresholds have increased seizure risk.
Infants under 1 year old should use this product with caution.
2. The long-term use of this product, should pay attention to the formation of drug resistance or drug dependence, treatment should not exceed the treatment needs. And this product is not suitable as an alternative treatment drug.
Although it is an opioid agonist, it does not inhibit the withdrawal symptoms of morphine.
3. In the case of commonly used quantities, this product may also affect the patient's ability to drive or mechanically operate.
4. Respiratory depression may occur if the dose exceeds the prescribed dose or is combined with central nervous system sedatives.
5. In patients with impaired liver and kidney function, the half-life is prolonged and the interval between medications should be appropriately extended.
6. Careful use of heart disease, as appropriate.
7. According to the relevant regulations of the National Pharmaceutical Administration Department, this product is strictly prohibited for food, feed processing and breeding.

Product foto





Our factory
This product is produced in our GMP factory, all our facility has past China GMP, and also officially certificated by more than ten countries' MOH. 




Our Service
We can specially develop the products per customers' specification.
We can offer OEM service with customers' private brands and labels.
We can offer excellent after-sale service and professional technical support.

Our Quality control system
In manufacturing, quality is what sustains our life.  Starting from the material selection, there are many factors that contribute to the quality control process.  Our manufacturing facility is GMP certified. Quality Control (QC) and monitoring procedures are built into every aspect of our work.
Our Quality Control System is outlined below:

1. Initial inspection (such as raw material, excipients, package materials, etc.)
2. In-process inspection (make sure that each testing items should be qualified )
3. Final inspection before shipment of each order. 
4. Provide temperature control recorder when it is necessary for special market before loading.

Our Registration Team and technical support
We have experienced team to provide qualified and professional registration documents for most of countries. Up to present, we have registered more than hundred products and exported to more than 20 countries. Especially including those in Asia, Africa, South America, Middle east area and East Europe.
We can provide regulatory documents

1. 1. GMP Certificate / CE Certificate
   2. Free sales certificate 
   3. Certificate of Pharmaceutical Products
   4. Manufacture License

CTD Dossier. 
  Tramadol hydrochloride sustained release tablet 100mg
Ingredients
The active ingredient of this product is tramadol hydrochloride.
Chemical name: (±)-E-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride.
Molecular formula: C16H25NO2·HCl
Molecular weight: 299.84
Character 
This product is white or almost white, one side has a dividing line of special-shaped film pieces.
Indications
For moderate to severe pain.
Specification 
100mg
Dosage
Swallow and do not chew.
The amount of this product depends on the degree of pain. It is generally taken from 50 mg (half tablet) each time and once every 12 hours. The dosage can be adjusted according to the patient's pain level. Normal adult and moderately painful patients over 14 years old, a single dose of 50 ~ 100mg (half -1 tablets). Children over 1 year of age who weigh not less than 25 kg are given a dose of 1 to 2 mg per kilogram of body weight. The minimum dose of this product is 50 mg (half tablet). The daily maximum dose usually does not exceed 400 mg (4 tablets). Higher doses may also be considered when treating cancer pain. Liver and kidney insufficiency should be used as appropriate. The dose of elderly patients should be considered reduced. The interval between two medications should not be less than 8 hours.
The above recommended dose is for reference only, in principle, the lowest dose of analgesia should be used. Take as directed by your doctor.
Adverse reactions
This product has adverse reactions:
1. Systemic: allergy, allergic reactions;
2. Cardiovascular system: hypotension, tachycardia, very rare hypertension and bradycardia;
3. Digestive system: nausea*, vomiting*, constipation*, gastrointestinal dysfunction, dry mouth*;
4. Central nervous system: dizziness*, drowsiness*, headache, visual abnormalities, emotional instability, euphoria, hypoactivity, hyperactivity, cognitive and sensory disturbances, convulsions, confusion, drug dependence, hallucinations, withdrawal synthesis Signs include: Excitement, anxiety, nervousness, insomnia, hyperkinesia, tremors, and gastrointestinal symptoms;
5. Skin: sweating*, pruritus, rash, urticaria, angioneurotic edema;
6. Urogenital system: urination disorders, urinary retention;
7. Respiratory system: dyspnea, bronchospasm, respiratory depression. (Note: * is a common adverse reaction with an incidence of ≥ 1%)
Contraindication 
People who are highly sensitive to this product and who are acutely poisoned by alcohol, sleeping pills, analgesics or other psychotropic substances.
Precautions
1. This product is used with caution in people who are opioid dependent or have drug abuse and dependence; acute alcoholism and use of sleeping pills, central analgesics (including opioids and psychotropic substances); in combination with central nervous system sedatives and When shock occurs; Monoamine oxidase inhibitors are being used or used within the past 14 days; Severe liver or kidney function damage; Head injury, increased intracranial pressure, confusion of unclear consciousness, respiratory and respiratory disorders, and respiratory depression.
Seizures have been reported to occur at therapeutic doses, and the risk of seizures may increase when the dose exceeds the conventional daily dose limit. For patients with a history of epilepsy or who are prone to attack, use it only as a last resort. Patients taking both tramadol and drugs that reduce seizure thresholds have increased seizure risk.
Infants under 1 year old should use this product with caution.
2. The long-term use of this product, should pay attention to the formation of drug resistance or drug dependence, treatment should not exceed the treatment needs. And this product is not suitable as an alternative treatment drug.
Although it is an opioid agonist, it does not inhibit the withdrawal symptoms of morphine.
3. In the case of commonly used quantities, this product may also affect the patient's ability to drive or mechanically operate.
4. Respiratory depression may occur if the dose exceeds the prescribed dose or is combined with central nervous system sedatives.
5. In patients with impaired liver and kidney function, the half-life is prolonged and the interval between medications should be appropriately extended.
6. Careful use of heart disease, as appropriate.
7. According to the relevant regulations of the National Pharmaceutical Administration Department, this product is strictly prohibited for food, feed processing and breeding.

Product foto





Our factory
This product is produced in our GMP factory, all our facility has past China GMP, and also officially certificated by more than ten countries' MOH. 




Our Service
We can specially develop the products per customers' specification.
We can offer OEM service with customers' private brands and labels.
We can offer excellent after-sale service and professional technical support.

Our Quality control system
In manufacturing, quality is what sustains our life.  Starting from the material selection, there are many factors that contribute to the quality control process.  Our manufacturing facility is GMP certified. Quality Control (QC) and monitoring procedures are built into every aspect of our work.
Our Quality Control System is outlined below:

1. Initial inspection (such as raw material, excipients, package materials, etc.)
2. In-process inspection (make sure that each testing items should be qualified )
3. Final inspection before shipment of each order. 
4. Provide temperature control recorder when it is necessary for special market before loading.

Our Registration Team and technical support
We have experienced team to provide qualified and professional registration documents for most of countries. Up to present, we have registered more than hundred products and exported to more than 20 countries. Especially including those in Asia, Africa, South America, Middle east area and East Europe.
We can provide regulatory documents

1. 1. GMP Certificate / CE Certificate
   2. Free sales certificate 
   3. Certificate of Pharmaceutical Products
   4. Manufacture License

CTD Dossier. 
 

Pain Relief Patch(Pain Areas)

Pain Relief Patch
[Name] Medical Cold Patch
[Package Dimension] 6cm×8cm 4pieces/box
The pain relief patch is composed of three layers, namely, backing lining, middle gel and protective film. It is free from pharmacological, immunological or metabolic ingredients.
[Scope of Application]
For cold physiotherapy, closed soft tissue only.
[Indications]
The patches give fast acting pain relief for strains, sprains, cramp, bruises, swollen areas or joint stiffness.
[How To Use a Patch]
Please follow the Schematic Diagram. One piece, one time.
The curing effect of each piece can last for 6-8 hours.
[Attention]
Do not apply the patch on the problematic skin, such as wounds, eczema, dermatitis,or in the eyes. People allergic to herbs and the pregnant are advised not to use the medication. If swelling or irritation occurs, please stop using and if any of these effects persist or worsen.notify your doctor or pharmacist promptly. Children using the patch must be supervised by adults.
[Storage Conditions]
Store below 30c in a dry place away from heat and direct sunlight.

Pain Relief Patch(Pain Areas),Shouler Pain Relief Patch,Joints Pain Relief Patch, Muscle Pain Relief Patch

Shandong XiJieYiTong International Trade Co.,Ltd. , https://www.sdxjmedical.com