In the past, people had always dreamed of transferring new drugs into the cow's body through genetic technology, turning each cow into a pharmaceutical factory. Today, scientists have turned this dream into a reality. On October 16th, China Agricultural University cooperated with Liangshan Kelon Animal Husbandry Industry Co., Ltd. of Shandong Province, the Animal Husbandry Institute of the Chinese Academy of Agricultural Sciences, Beijing Genda Technology Co., Ltd. and Hebei Lutai Farm and successfully obtained the first time through somatic cell cloning technology. The first batch of genetically modified cloned cattle in China, and the creation of two international for the first time, obtained the first somatic cell cloned cow for the human fucosyltransferase gene for the treatment of human gastric ulcer disease, and obtained the first transit in the same cow. Transgenic somatic cloned cattle with three foreign genes. According to Professor Li Ning, the chief scientist of the project at China Agricultural University, the project was successfully completed on March 25, 2003 with the support of the National “863†Program, the Beijing Municipal Government, and the Shandong Provincial Government. The first genetically modified cell cloned cow, Lewa, was obtained in China. On Oct. 4, 2003, the world’s first somatic cell clone, “Lanwaâ€, was successfully obtained. Li Ning introduced that the world's first genetically modified cow (human fucosyltransferase gene, green fluorescent protein gene, and neomycin resistance gene) that had three genes at the same time was successfully transferred to the “Rock Babyâ€. Fucosyltransferase gene". Fucosyltransferase is an important enzyme that catalyzes the formation of blood glucose antigens in the human body. Recent studies have found that the antigenic substances catalyzed by fucosyltransferases can specifically regulate the binding of H. pylori to human gastric epithelial cells. The Helicobacter pylori is an important pathogenic bacteria such as chronic superficial atrophic gastritis, peptic ulcer, gastric hyperplastic polyposis, and gastric cancer. It is listed as a carcinogenic agent by the International Health Organization. According to the World Health Organization, 50% to 80% of the world’s population is infected with Helicobacter pylori, and in China it reaches 70%. Because fucose antigens exist only in humans and primates, scientists have used genetically-translated cloning methods to transfer the human fucosyltransferase gene into the bovine genome, allowing it to express fucose antigens in milk. The resulting transgenic milk can be used as an oral drug to achieve the goal of treating or preventing stomach problems. This will have important implications for the prevention and treatment of global gastropathy. It can be said that this world's first case of a “rock baby†with “fucosyltransferase†will become invaluable.
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