Intraoperative floppy iris syndrome (IFIS) is one of the common complications in cataract surgery. Common manifestations: iris surge, prolapse, progressive diminution of the pupil. Iris trauma and posterior capsular rupture are common complications. At home and abroad commonly used preoperative atropine eye drops, the application of iris hooks, iris expansion ring, injection of epinephrine and other methods. A recent study showed that preoperative prophylactic use of phenylephrine can also achieve good results.
It is generally believed that IFIS is associated with &alphara;-1 adrenergic receptor antagonists, especially tamsulosin, a drug commonly used for benign prostatic hyperplasia.
A recent meta-analysis showed that patients taking tamsulosin have a 43% to 90% chance of developing IFIS - and a new study suggests that anterior chamber injection of 1.5% phenylephrine can effectively improve this condition.
At the beginning of surgery, one eye of 42 patients received 1.5% phenylephrine and the other received normal saline. All the operations were completed without any adverse reactions. Eyes given phenylephrine had no IFIS indications, compared to 88% in the saline control group. Of these eyes, 55% had significant pupillary diminution, prolapse of the iris, or both.
Researchers believe that if patients are aware of the relevant risks in advance, they can prevent medication; if patients do not report the use of &alPHa; -1 receptor antagonists, and IFIS occurs during surgery, injection of phenylephrine can effectively reverse the symptoms and restore The iris is rigid and induces the pupil to regain its size, preventing the iris from prolapse.
It is generally believed that IFIS is associated with &alphara;-1 adrenergic receptor antagonists, especially tamsulosin, a drug commonly used for benign prostatic hyperplasia.
A recent meta-analysis showed that patients taking tamsulosin have a 43% to 90% chance of developing IFIS - and a new study suggests that anterior chamber injection of 1.5% phenylephrine can effectively improve this condition.
At the beginning of surgery, one eye of 42 patients received 1.5% phenylephrine and the other received normal saline. All the operations were completed without any adverse reactions. Eyes given phenylephrine had no IFIS indications, compared to 88% in the saline control group. Of these eyes, 55% had significant pupillary diminution, prolapse of the iris, or both.
Researchers believe that if patients are aware of the relevant risks in advance, they can prevent medication; if patients do not report the use of &alPHa; -1 receptor antagonists, and IFIS occurs during surgery, injection of phenylephrine can effectively reverse the symptoms and restore The iris is rigid and induces the pupil to regain its size, preventing the iris from prolapse.
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