Pharmaceutical Antiobesity Agent Raw Powder Orlistat for Weight Loss

• Model NO.: 96829-58-2
• Customized: Non-Customized
• Suitable for: Adult
• Purity: >99%
• CAS: 96829-58-2
• MW: 495.73
• Melting Point: <50 °c
• Delivery Time: Within 24 Hours After We Get Your Payment
• Transport Package: Discreet Package
• Origin: China

• Powder: Yes
• Certification: HSE, ISO 9001
• State: Solid
• Synonym: Orlipastat
• Mf: C29h53no5
• Appearance: White or Kind of White Crystalline Powder
• Usage: Used for Curing Obesity.
• Trademark: Saichuang
• Specification: Enterprise standard

Pharmaceutical Antiobesity Agent Raw Powder Orlistat For Weight Loss


Basic Information

What is Orlistat?

Orlistat is a white to off-white crystalline powder. Orlistat is practically insoluble in water, freely soluble in chloroform, and very soluble in methanol and ethanol. Orlistat has no pKa within the physiological pH range.

Orlistat is a drug that promotes loss of weight by preventing the digestion and absorption of fat in food. In the intestine, an enzyme called lipase (produced primarily by the pancreas) breaks apart fat in food so that it can be absorbed into the body. Orlistat blocks the action of lipase and thereby prevents the breakup and absorption of fat. Orlistat blocks absorption of about 25% of the fat in a meal. The unabsorbed fat is excreted in the stool. The FDA approved Orlistat by prescription in 1999. 

Description

Orlistat (also known as tetrahydrolipstatin) is a drug designed to treat obesity. It is marketed as a prescription drug under the trade by Roche in most countries, and is sold over-the-counter as Alli by GlaxoSmithKline in the United Kingdom and the United States.Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet.

Orlistat is the saturated derivative of lipstatin, a potent natural inhibitor of pancreatic lipases isolated from the bacterium Streptomyces toxytricini.However, due to its relative simplicity and stability, orlistat was chosen over lipstatin for development as an anti-obesity drug.

Application

The effectiveness of orlistat in promoting weight loss is definite, though modest. Pooled data from clinical trials suggest that people given orlistat in addition to lifestyle modifications, such as diet and exercise, lose about 2-3 kilograms (4.4-6.6 lb) more than those not taking the drug over the course of a year.Orlistat also modestly reduces blood pressure, and appears to prevent the onset of type 2 diabetes, whether due to weight loss itself or to other effects; in a large randomized controlled trial, orlistat was found to reduce the incidence of diabetes by nearly 40% in obese people.

Orlistat is notorious for its gastrointestinal side effects (sometimes referred to as treatment effects), which can include steatorrhea (oily, loose stools). These decrease with time, however, and are the most frequently reported adverse effects of the drug.In the United States and the European Union, orlistat is available for sale without a prescription. Over-the-counter approval was controversial in the United States, with consumer advocacy group Public Citizen repeatedly opposing it on safety and efficacy grounds.Generic formulations of orlistat are available in some countries. In Australia it is listed as an S3 medication, which means it's available over the counter in pharmacies.


COA

Usage

1. An antiobesity agent. A pancreatic lipase inhibitor. Antiobesity agent.

2. Antidiabetic

3. Orlistat is an antiobesity agent. Orlistat is an pancreatic lipase inhibitor.

4. Tetrahydrolipstatin (orlistat) is a semi-synthetic derivative of lipstatin, a metabolite isolated from Streptomyces toxytricini. Tetrahydrolipstatin acts as a potent, irreversible inhibitor of pancreatic lipase. In vivo, it blocks the absorption of triglycerides while allowing fatty acid absorption. Tetrahydrolipstatin is widely used for the
treatment of obesity.


Advantage

1. We have experience in exporting Pharma Chemicals, as you know, EU places much emphasis on them, and you must find a experienced partner who will assure you;

2. Quality: Our company is a professional leading factory in China in pharmaceutical area, We had stable customers and exported to Germany, Spain, UK, USA, Australia, Middle East, and any other countries. We can provide good references about our company. As for the quality of the products, we 're sure they can satisfy you well enough;

3. Package: Professional packing with professional materials

4. Delivery: We have products in stock, and we will deliver them soon when your PO arrived. Meanwhile we will give you the tracking number in order to make you know the exact location of the products. We will keep track of the product until they arrive you; We choose the best courier service for you, and with the delivery around 5-7 working days.

5. Service: Best Service with after-sales service and consultation!

 

Roughness Profilometer

Roughness Profile Measuring Instruments all-in-one machine is an all-in-one machine for measuring profile shape and surface roughness, which has the powerful function of analyzing and measuring profile shape and surface roughness. Realize accurate measurement of dimensions, shape and roughness. It is mainly used to measure the parameters of the surface micro-geometry and macro-geometry of mechanical parts such as straightness, inclination, angle treatment, roundness treatment, double-groove treatment, double-arc treatment, etc.

Performance characteristics
1. High accuracy, high stability and high repeatability: meet the measurement accuracy requirements of the measured part.
1) Select high-precision grating measurement system and high-precision inductance measurement system, with high measurement accuracy;
2) Independently researched and developed high-precision grinding guide rail system, which has good wear resistance of guide rail materials and ensures stable and reliable operation of the system;
3) High-performance linear motor drive system ensures high measurement stability and good repeatability.
2. Intelligent management and detection software system:
The operation interface of the instrument is friendly, the operator can easily master the operation of the instrument, and the use is very simple.
1) The company has accumulated many years of practical measurement software design experience to provide customers with simple, practical and fast operation experience;
2) The company has invested many years of human resources in the development of instrument software, with special software copyright;
3) With powerful functions, it can automatically process data, print reports in various formats, and automatically display, print, save and query measurement records;
The data can be archived or printed in a centralized manner, which does not take up the verification operation time;
4) The measurement range is wide, which can meet almost all types of workpiece profile measurement, including special measurement functions of special workpiece screw, bearing, thread and other profiles;
5) The measured section can be selected automatically and manually for evaluation, and software functions can be customized according to customer requirements;
6) Powerful CNC automatic measurement and automatic labeling analysis function;
For large quantities of the same type of workpiece, it can carry out CNC measurement, automatically analyze and process the data, and carry out SPC statistics on the data, and can carry out statistical analysis in various ways to give quality control guidance;
7) It can automatically record and save all verification results by using computer large-capacity database storage.
3. It can also measure surface roughness and contour shape
With the same main body, you can only switch different modules to measure the profile shape and microroughness of the product.
4. Multi-parameter evaluation
The roughness can be automatically evaluated according to different standards, including Ra, Rp, Rv, Rz, Rt, Rmax, Rq, Rsk, Rku, RSm, RPc, Rdq, Rdc, Rmr and P parameters, W parameters, Motif parameters, Rcore parameters and other multi-parameter evaluation.
5. Thickness parameter measurement
When measuring the roughness parameters, the height and thickness of some film steps within 600 microns can be measured simultaneously. The measurement is convenient, and the accuracy is controlled within 2% H (H, the total height of measurement). It is especially suitable for high-precision measurement occasions without scratches.
6. Measuring force system:
With the voice coil motor force measuring system, the force measurement can be continuously adjustable from 10 to 150 mN, and the force measurement resolution can reach 0.2 mN; It avoids the force measurement error caused by the vibration of the surrounding environment when the old weight is loaded, and reduces the measurement error caused by the change of the force measurement.
7. Intelligent protection system:
The instrument is protected by hardware and software in all directions, which can effectively protect the instrument host and probe, and reduce the probe and instrument damage caused by personnel's operation errors.
8. Flexible manual control:
The instrument is equipped with a special separating operating rod, which can be placed at any position to control the operation when the instrument is operated and moved, and the measuring needle can be roughly positioned before measuring the workpiece; In the case of leaving the computer, the operating rod has the functions of moving the measuring needle left and right/up and down, emergency stop, the angle swing of the measuring rod up and down, and multi-level speed adjustment.

Profile Measuring Instruments,Profilometer Accuracy,Profile Measuring Machine,Surface Profile Measurement

Zhejiang dexun instrument technology co., ltd , https://www.dexunmeasuring.com