Release date: 2017-10-10
Recently, a research report published in the international journal Nature Biomedical Engineering, researchers from the Caroline College and Caroline University Hospital in Sweden developed a new type of microscope technology, compared to the current two-dimensional method. In this way, this new technology can detect tumor tissue in a three-dimensional environment and more accurately diagnose cancer.
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Every day, pathologists all over the world test a large number of tumor tissues, and the results can promptly guide cancer patients for treatment. However, sometimes scientists have difficulty in accurately diagnose cancer, which means patients may be given errors. The treatment method, which delays the disease and even causes the patient to die.
The current pathological detection methods for assessing the stage of tumor development usually use two-dimensional optical microscopy. The cancer stage can describe the development and spread of cancer. It is very important to timely and accurately treat patients, and use this method to perform three-dimensional analysis of cancer tissues. It is not the best to only see the realization of two-dimensional observations, and often leads to information gaps.
Researcher Per Uhlen said that in individual studies, tumors are divided into multiple parts, but three-dimensional structures such as blood and lymphatic systems are very difficult to analyze. In this study, researchers used a new imaging technique to study humans. Tumor tissue, a technique that makes tumor tissue transparent, and then researchers can perform three-dimensional replication of tumor tissue under so-called light-sheet microscopy. By using special antibodies, researchers Special proteins can be labeled and analyzed more finely.
This kind of light illumination microscope is usually used in basic research, but in recent years researchers have improved it to be used in hospital clinical practice. In this paper, researchers use this technology to conduct the first internal environment of the patient's tumor tissue. Analytical research. Using this technology, researchers can study tumor samples from patients with stored bladder cancer, and then use a three-dimensional blood supply system to nourish the tumor. The results show that these structures can well explain the invasiveness of the tumor. At the same time, this new three-dimensional microscopy technology can diagnose tumors invading muscles with higher accuracy.
In addition, the researchers also studied other cancer types to determine whether this new technology can be used as a clinical diagnosis of all types of solid tumors, especially for tumors that are difficult to diagnose. Researchers hope that one day in the future More pathological detection studies can be performed using 3D imaging technology.
Source: Bio Valley (WeChat: BIOONNEWS)
China has become the world's largest producer of Antipyretic And Analgesic drugs. The output of aspirin, paracetamol, analgin and other varieties has exceeded 10,000 tons, and the output of phenacetin, aminopyrine, antipyrine and other varieties has exceeded 1,000. Ton. At present, the output of Antipyretic analgesics in my country is growing rapidly, and it is expected to grow at a rate of about 8% in the future. The production of intermediates for antipyretic and analgesic drugs is large, and there are many manufacturers. With the growth of antipyretic and analgesic drugs, their intermediates have also developed by leaps and bounds.
In 2003, the domestic consumption of paracetamol increased rapidly, and the export also showed a rapid growth momentum. The export volume was 28,163 tons, and the annual export volume increased by about double. In the first half of 2004, although its export growth slowed down, it still increased. From January to May 2004, the export volume of paracetamol was 12,501 tons, slightly higher than the same period last year. Para-aminophenol is an important intermediate in the synthesis of paracetamol, which is growing rapidly. The annual output of p-aminophenol in my country is 32,000 tons. It is estimated that by 2005, the domestic production of paracetamol will reach more than 50,000 tons, and the pharmaceutical industry will consume 45,000 tons of p-aminophenol. The total demand for phenol is about 50,000 tons, the market gap is large, and the development and utilization prospects are broad.
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