The dry granulator is a fully enclosed dry granulation system that reduces the risk of hygiene problems by reducing the amount of contamination in the production process. The equipment can choose different angles of granulating knives according to the nature of the customer's materials. During the granulation process, the fluting process is ensured, and the phenomenon that the materials do not turn up, roll, and turn during the granulation process is solved.
The production of various types of feed pellets relies on the safe operation of the dry granulator. The formation of the pellets depends on two aspects, on the one hand depending on the effective use and transfer of the applied external force, and on the other hand on the particulate material. Physical properties. But the inevitable one is that there are a series of problems in using dry granulation:
1, made the particles too hard
In the dry granulation process, if the pressure of the press roll is too high, the pressed particles are too hard, resulting in a decrease in the compressibility of the granules, and in the subsequent tableting, a large pressure is required to press-form, or the obtained tablet. The hardness is small; when some of the particles are too hard, it is easy to produce a flower phenomenon. When the dry particles are too hard, the particles are also difficult to dissolve in water, which affects the disintegration of the particles.
2, the roundness of the particles is low
The roundness of the particles directly affects the flowability of the particles. The roundness of the granules obtained by dry granulation is slightly worse than that of the wet granulation, but the roundness of the granules can be controlled by adjusting the sheet thickness of the dry granulator and the structure of the finisher during granulation. .
3. The fine powder of the granules after granulation is still more
Poor compressibility of materials, replacement of compressible materials such as: microcrystalline cellulose, pregelatinized starch
The amount of the binder is small, and the amount of the binder is increased; the pressure of the pressure roller is small, the tablet is brittle, and the pressure of the pressure roller or the feed speed is increased.
4, material pressure roller
The amount of lubricant in the material is small, and the amount of lubricant should be increased. However, the total amount of lubricant should be noted. Under the premise of improving or resolving the material pressure roller, it can be added less. The hygroscopic material in the material also causes the material to stick to the pressure roller.
5, the feeding discontinuity during the granulation process causes the extruded sheet to be discontinuous
The fluidity of the raw materials is too poor after mixing, and the flow aid is added to the materials or materials with good fluidity.
Use multiple granulation methods (note that some materials such as microcrystalline cellulose are not suitable for anti-replicating particles), the material or part of the material should be granulated first to increase the fluidity of the material.
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