Recently, the State Food and Drug Administration issued a message on its official website that the Henan Provincial Jiaozuo Health Yuan Bio-products Co., Ltd. (hereinafter referred to as Jiaozuo Health Yuan) suspected the purchase of more than 100 million yuan of waste oil for the production of pharmaceutical raw materials.
"Daily Economic News" reporter learned from the State Food and Drug Administration that the bureau has dispatched an investigation team to conduct investigations. At the same time, it requires the pharmaceutical companies to strictly monitor the purchased raw materials in accordance with regulations, conduct audits on supply companies, and prevent entry of unqualified chemical raw materials. Pharmaceutical links.
An insider of the State Food and Drug Administration stated that the investigation had begun and the investigation team set up by the Jiaozuo City Government had played a leading role. The State Food and Drug Administration sent personnel to participate, mainly playing the role of coordination and supervision. According to the source, it is not yet convenient to disclose specific investigation results. If there is any news, it will be disclosed to the public in a timely manner.
The person in charge of the Press and Propaganda Branch of the Jiaozuo Municipal Party Committee Propaganda Department of Henan Province said in an interview with the reporter of the “Daily Economic News†yesterday that the municipal party committee and the municipal government attached great importance to this matter. After public opinion was exposed, on the afternoon of August 30th, the municipal government quickly established four investigation teams and sent quality inspection, industry and commerce, drug supervision and other departments to participate in the investigation. Up to now, the investigation work has progressed smoothly, but no detailed investigation results have been issued. He said that in view of the fact that the issue involves professionalism, although there is already a preliminary conclusion, it still requires the authoritative organization's determination, and it needs an assessment process. It will take the initiative to contact the media and inform them of the appropriate timing.
At present, the personnel dispatched by the State Food and Drug Administration and the investigation team of the Jiaozuo City Government have jointly entered the enterprises involved. A staff member of the Surname Family Office of the Henan Bureau of Food and Drug Control stated that the argument of “ditch oil pharmaceutical†is not accurate. 7-ACA is an intermediate for the production of cephalosporin antibiotics and belongs to chemical raw materials. There are two steps for chemical companies to produce 7-ACA: First, cephalosporin C is obtained through cephalosporin fermentation. Soybean oil is one of the components of the fermentation process. Soybean oil mixed with waste oil components is used in this step; the second step The enzymatic or chemical cleavage method is used to separate and purify 7-ACA. Health Yuan purchases waste oil, which is used to make 7-ACA chemical raw materials, that is to say, waste oil is used as a chemical raw material for culture media. It also requires complicated and delicate manufacturing processes, including derivatization, protection, access to side chains, deprotection and Salt, as well as separation, purification, recrystallization and other steps, to become cephalosporin antibiotic raw materials, and then through the preparation process, can produce oral, injectable cephalosporin antibiotic drugs. Therefore, the use of waste oil to make 7-ACA behavior, "will not cause harmful effects on the human body, it is still not easy to say."
However, several experts have publicly stated that the composition of waste oil is complex. According to the existing technology, it is impossible to know which harmful or carcinogenic substances are contained inside. The risk of using souvrowth oil instead of soybean oil is not well-assessed.
In this regard, the State Drug Administration said that it is organizing experts to retrieve relevant domestic and foreign literature to assess the impact of soybean oil quality on the quality and safety of cephalosporin antibiotics and to understand the practice of using recycled oil abroad.
Earlier, according to media reports, the nation’s first rigorous waste oil case was heard in the Ningbo Intermediate People’s Court on August 22nd. This led to a heavy insider: Jiaozuo Health Yuan continuously purchased cooking oil for a year and a half. For the production of 7-ACA, this batch of products has also been widely flown to the pharmaceutical market. It is reported that such health products, occupy a quarter of the total market. Subsequently, Health Yuan issued an announcement on its official website that Henan Huikang Oil & Grease Co., Ltd., when selling soybean oil to users of soybean oil including healthy ingredients, was doped with inferior product oil including waste oil. situation".
With the opening of the production and sales of waste oil and its related product chain, Henan Huikang was exposed to the sale of oil products containing waste oil, totaling nearly 300 million yuan, while Jiaozuo Health Yuan was the largest buyer of Henan Wellcome. In a year and a half, the purchase amounted to RMB 145 million for the production of 7-ACA.
According to the 2011 annual report of Health Yuan, the company’s total sales to the top five customers were 369.33 million yuan, accounting for 7.8% of the main business income; in 2010, the company’s total sales to the top five customers were 420.53 million yuan, accounting for the main business revenue. 9.52%.
"Daily Economic News" reporter learned from the State Food and Drug Administration that the bureau has dispatched an investigation team to conduct investigations. At the same time, it requires the pharmaceutical companies to strictly monitor the purchased raw materials in accordance with regulations, conduct audits on supply companies, and prevent entry of unqualified chemical raw materials. Pharmaceutical links.
An insider of the State Food and Drug Administration stated that the investigation had begun and the investigation team set up by the Jiaozuo City Government had played a leading role. The State Food and Drug Administration sent personnel to participate, mainly playing the role of coordination and supervision. According to the source, it is not yet convenient to disclose specific investigation results. If there is any news, it will be disclosed to the public in a timely manner.
The person in charge of the Press and Propaganda Branch of the Jiaozuo Municipal Party Committee Propaganda Department of Henan Province said in an interview with the reporter of the “Daily Economic News†yesterday that the municipal party committee and the municipal government attached great importance to this matter. After public opinion was exposed, on the afternoon of August 30th, the municipal government quickly established four investigation teams and sent quality inspection, industry and commerce, drug supervision and other departments to participate in the investigation. Up to now, the investigation work has progressed smoothly, but no detailed investigation results have been issued. He said that in view of the fact that the issue involves professionalism, although there is already a preliminary conclusion, it still requires the authoritative organization's determination, and it needs an assessment process. It will take the initiative to contact the media and inform them of the appropriate timing.
At present, the personnel dispatched by the State Food and Drug Administration and the investigation team of the Jiaozuo City Government have jointly entered the enterprises involved. A staff member of the Surname Family Office of the Henan Bureau of Food and Drug Control stated that the argument of “ditch oil pharmaceutical†is not accurate. 7-ACA is an intermediate for the production of cephalosporin antibiotics and belongs to chemical raw materials. There are two steps for chemical companies to produce 7-ACA: First, cephalosporin C is obtained through cephalosporin fermentation. Soybean oil is one of the components of the fermentation process. Soybean oil mixed with waste oil components is used in this step; the second step The enzymatic or chemical cleavage method is used to separate and purify 7-ACA. Health Yuan purchases waste oil, which is used to make 7-ACA chemical raw materials, that is to say, waste oil is used as a chemical raw material for culture media. It also requires complicated and delicate manufacturing processes, including derivatization, protection, access to side chains, deprotection and Salt, as well as separation, purification, recrystallization and other steps, to become cephalosporin antibiotic raw materials, and then through the preparation process, can produce oral, injectable cephalosporin antibiotic drugs. Therefore, the use of waste oil to make 7-ACA behavior, "will not cause harmful effects on the human body, it is still not easy to say."
However, several experts have publicly stated that the composition of waste oil is complex. According to the existing technology, it is impossible to know which harmful or carcinogenic substances are contained inside. The risk of using souvrowth oil instead of soybean oil is not well-assessed.
In this regard, the State Drug Administration said that it is organizing experts to retrieve relevant domestic and foreign literature to assess the impact of soybean oil quality on the quality and safety of cephalosporin antibiotics and to understand the practice of using recycled oil abroad.
Earlier, according to media reports, the nation’s first rigorous waste oil case was heard in the Ningbo Intermediate People’s Court on August 22nd. This led to a heavy insider: Jiaozuo Health Yuan continuously purchased cooking oil for a year and a half. For the production of 7-ACA, this batch of products has also been widely flown to the pharmaceutical market. It is reported that such health products, occupy a quarter of the total market. Subsequently, Health Yuan issued an announcement on its official website that Henan Huikang Oil & Grease Co., Ltd., when selling soybean oil to users of soybean oil including healthy ingredients, was doped with inferior product oil including waste oil. situation".
With the opening of the production and sales of waste oil and its related product chain, Henan Huikang was exposed to the sale of oil products containing waste oil, totaling nearly 300 million yuan, while Jiaozuo Health Yuan was the largest buyer of Henan Wellcome. In a year and a half, the purchase amounted to RMB 145 million for the production of 7-ACA.
According to the 2011 annual report of Health Yuan, the company’s total sales to the top five customers were 369.33 million yuan, accounting for 7.8% of the main business income; in 2010, the company’s total sales to the top five customers were 420.53 million yuan, accounting for the main business revenue. 9.52%.
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