Medicinal effect
It has the effect of dispelling wind and dispelling cold, stopping pain, and warming the lungs.
1. The sedative and analgesic effects of Asarum volatile oil have obvious central inhibition. Small doses can make animals quiet, tamed, and reduce their autonomic activities. Large doses can make animals sleep and have significant anticonvulsant effects. Asarum decoction gavage also has analgesic effect. Its strong analgesic effect is an important pharmacological basis for treating head pain and toothache.
2. Antipyretic effect of Astaxanthin volatile oil for a variety of reasons such as the method of temperature, tetrahydro-β-naphthylamine, typhoid fever, paratyphoid mixed vaccine caused by experimental fever in rabbits has a significant antipyretic effect, caused by the brewer's yeast The fever of rats also has a significant antipyretic effect. It also reduces body temperature in normal rats.
3. Anti-inflammatory, immunosuppressive and anti-allergic effects of Aspergillus essential oil perfusion or injection have obvious anti-inflammatory effects. Such as Asarum on inflammation of the carrageenan, yeast, egg white, formaldehyde, etc. caused by rat joint swelling significantly inhibited, and can be croton oil-induced mouse ear swelling, inhibition of anti-serum caused by large Rat skin edema, increase in capillary permeability caused by histamine, and inhibition of plastic ring and pellet proliferation. There is still an anti-inflammatory effect on rats that are adrenal glands.
The effective components of Asarum, methyl eugenol, N-isobutyldodecandiamide and norcoclaurine, can significantly inhibit histamine-induced rat ileum contraction. Aspartame or alcohol extracts can reduce the total allergic media release of immediate allergy by more than 40%, indicating that it has anti-allergic effects.
4. Enhancing the Body's Metabolic Function Racemic nor-auroraine isolated from Asarum has a wide range of pharmacological effects like beta-agonists. It has a strong heart, dilates blood vessels, relaxes smooth muscles, enhances lipid metabolism and increases blood sugar, etc. effect. It is known that azithromycin is contained in a variety of medicines that are warm and warm, such as Asarum, Aconite, and Evodiae. The pharmacological effects they present are consistent with the efficacy of Chinese herbs in dispersing cold or dispelling cold, so they can be considered as scattered. One of the important material bases of cold efficacy.
5. Asthma, expectorant effect Asarum can relax bronchial smooth muscle and show asthma effect. In vitro experiments have shown that volatile oil of Asarum has significant antagonistic effects on bronchospasm caused by histamine and acetylcholine; its volatile oil component, methyl eugenol, also has significant relaxation effects on the rat trachea. Asaron also has a certain asthma, expectorant effect. In addition, its alcoholic infusion intravenously against morphine-induced respiratory depression.
6. Cardiotonic, anti-myocardial ischemia, ascending blood pressure Asarum has a cardiotonic, anti-ischemic, and hypertensive effect. In vitro experiments showed that Asarum volatile oil has significant stimulant effect on rabbit and pulsatile heart, showing positive inotropic strength, positive frequency effect, and can increase coronary flow. For dogs with experimental cardiogenic shock, Asarum can increase its mean arterial pressure, peak left ventricular pressure, and coronary sinus flow, and its effect is similar to that of dopamine, but it does not accelerate the heart rate.
Aspartame volatile oil is given intravenously to anesthetized dogs and cats, and the antihypertensive effect can be seen, but its decoction has a significant pressure-increasing effect, and its boosting effect may be related to adefovir dipivoxil.
7. Antibacterial and antiviral effects of octanol infusion, volatile oil, etc. have certain inhibitory effects on Gram-positive bacteria, Bacillus subtilis, and Salmonella typhi in vitro. The decoction also has inhibitory effects on Mycobacterium tuberculosis and Salmonella typhi. Asarum volatile oil has inhibitory effects on many fungi such as Aspergillus flavus, Aspergillus niger and Candida albicans. The effective antibacterial ingredient is astragaloside. Alpha-asarone can inhibit the proliferation of respiratory syncytial virus.
8. Local Anesthesia 50% Asarum decoction can block the sciatic nerve impulse conduction, the effect is reversible. Its anesthetic effect is similar to that of 1% procaine. Volatile oil has surface anesthesia, infiltration and anesthesia. 50% of Asarum applied to human tongue also has local anesthetic effect.
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